Meatloaf Cheddar Shells Casserole

Featured in: Hearty and Delicious Meals

This dish features a savory ground beef and breadcrumb base seasoned with garlic and onion powder, pressed into a casserole for a satisfying foundation. Tender pasta shells are tossed with sharp cheddar cheese, creamy tomato soup, and milk, then layered over the meat for a rich, hearty topping. Baked until bubbly and golden, this comforting meal combines classic meatloaf flavors with creamy, cheesy pasta for a family-friendly favorite that’s both filling and easy to prepare.

Tags: #halal #baked #family-friendly #north-american #easy #over-30-minutes #dinner

sana kitchen chef
By Sana Sana
Updated on Sat, 06 Sep 2025 09:55:03 GMT
A delicious Meatloaf & Cheddar Shells Casserole is ready to be served. Pin it
A delicious Meatloaf & Cheddar Shells Casserole is ready to be served. | recipebyme.com

This family size casserole checks all the comfort food boxes with a juicy meatloaf foundation and a lusciously creamy cheddar shell topping. It comes together with a handful of affordable pantry-friendly ingredients, bakes up golden and bubbly, and will have everyone asking for seconds on a chilly weeknight.

The first time I whipped this up I needed something cozy with minimal effort. It instantly became a crowd pleaser that saved many busy evenings in our home.

Ingredients

  • Ground beef: choose freshly ground beef with a little fat for juiciness and flavor
  • Breadcrumbs: use fine crumbs for better mixing and lighter texture
  • Garlic powder: for bold aroma and background depth
  • Onion powder: for subtle allium notes without chopping
  • Salt and pepper: basic seasoning to bring out all the flavors
  • Medium pasta shells: their shape catches the cheesy sauce beautifully
  • Shredded cheddar cheese: go for sharp cheddar for excellent melting and tang
  • Condensed tomato soup: gives creamy tang and body to the topping
  • Milk: helps achieve a smooth, pourable sauce try whole milk for creamier results

Instructions

Prep the Oven:
Preheat your oven to 350 degrees Fahrenheit which ensures an even bake and perfect bubbling cheese. Grease a nine by thirteen inch baking dish well to prevent sticking.
Mix and Layer Meatloaf:
In a large mixing bowl combine ground beef breadcrumbs garlic powder onion powder salt and pepper. Gently mix by hand until just combined to avoid tough meat. Press this mixture evenly into the bottom of your prepared baking dish forming a solid base. Level out the surface so it cooks consistently.
Blend Cheddar Shell Layer:
Boil your pasta shells until al dente drain well then transfer to a bowl. Add shredded cheddar cheese condensed tomato soup and milk. Stir until every shell is coated with a creamy cheesy mixture.
Spread and Layer:
Carefully spoon the cheddar shell mixture over the meatloaf base. Use a spatula to spread it in an even layer making sure every bite will have both meat and cheesy pasta.
Bake and Finish:
Cover the casserole with foil to keep in moisture and bake for thirty minutes. After that remove foil and continue baking for another ten to fifteen minutes until the top is bubbly and golden brown. Rest for five to ten minutes before slicing so everything sets up and serves neatly.
A delicious macaroni and cheese dish is served in a white bowl.
A delicious macaroni and cheese dish is served in a white bowl. | recipebyme.com

Cheddar cheese is always the centerpiece here. I have fond memories of my grandma grating a mountain of sharp cheddar for her casseroles adding that nostalgic and tangy flavor that simply ties it all together around the table.

Storage Tips

Let leftovers cool completely before covering tightly or transferring to containers. It keeps well in the fridge for up to three days and reheats beautifully in the oven or microwave with a splash of milk to refresh the sauce.

Ingredient Substitutions

Swap ground beef with ground turkey or a plant-based crumble for a lighter take. Any small pasta shapes work if shells are unavailable and mozzarella can replace cheddar for a milder finish. If tomato soup is not on hand try a can of marinara blended with a splash of cream.

Serving Suggestions

Serve slices with a fresh green salad or roasted vegetables to balance the richness. Warm garlic bread is always a winning side. For family gatherings it pairs well with steamed broccoli or corn on the cob.

Cultural Context

This casserole is classic American comfort food blending beloved flavors of meatloaf and macaroni and cheese in one dish. It emerged as an easy way to stretch ground meat and pantry staples into a hearty all-in-one meal.

Seasonal Adaptations

Add a layer of diced roasted veggies such as zucchini or bell pepper in summer. Boost flavor with smoked paprika or fresh thyme in winter. Mix in a spoonful of mustard to the meat mix for tangy brightness. My favorite way is to tuck in chopped cooked spinach between the layers for extra greens but the base recipe really shines as written.

Success Stories

A friend once made a double batch using leftover pork meatloaf and it turned out just as delicious. My kids love packing slices in their lunchboxes since it holds up well and tastes great at room temp. I even froze single servings for my own go to quick dinners in busy weeks.

Freezer Meal Conversion

Before baking you can cover tightly with plastic wrap and foil then freeze for up to two months. Thaw overnight in the fridge and bake as directed. Baking from frozen will take extra time but still gives great results. This trick saved me many winter nights when I wanted home-cooked comfort with zero last minute work.

A plate of pasta with meat and cheese on top.
A plate of pasta with meat and cheese on top. | recipebyme.com

This hearty casserole brings warmth to any table and is sure to become a regular request. Enjoy the melding of nostalgic flavors and easy meal magic that comes with every slice.

Recipe FAQs

→ How do I keep the beef layer moist?

Mix the beef gently with breadcrumbs and seasonings to retain moisture and avoid overworking the meat.

→ Can I use different pasta shapes?

Medium pasta shells are ideal, but elbow macaroni or penne also work well for this casserole.

→ What type of cheese melts best in this dish?

Shredded cheddar provides great flavor and creaminess, though a blend with mozzarella can add extra melt.

→ Is it possible to prepare ahead?

Yes, assemble the dish up to a day in advance and refrigerate; bake before serving as directed.

→ How should leftovers be stored?

Cool completely, cover, and refrigerate for up to 3 days. Reheat portions in the oven or microwave until hot.

Meatloaf Cheddar Shells Casserole

Savory beef and breadcrumbs baked under cheddar pasta shells in tomato sauce for comforting family meals.

Prep Time
15 min
Cook Time
40 min
Total Time
55 min
By Sana: Sana

Category: Main Dishes

Skill Level: Easy

Cuisine: American

Yield: 6 Servings (One 9×13-inch casserole)

Dietary Categories: ~

Ingredients

→ For the meat base

01 1 pound ground beef
02 1/2 cup breadcrumbs
03 1/2 teaspoon garlic powder
04 1/2 teaspoon onion powder
05 Salt, to taste
06 Black pepper, to taste

→ For the cheddar shells topping

07 8 ounces medium pasta shells, cooked and drained
08 1 cup shredded cheddar cheese
09 1 can (10.75 ounces) condensed tomato soup
10 1 cup whole milk

Steps

Step 01

Preheat oven to 350°F (175°C). Grease a 9×13-inch baking dish with nonstick spray or butter.

Step 02

In a large mixing bowl, combine ground beef, breadcrumbs, garlic powder, onion powder, salt, and black pepper. Gently mix until evenly incorporated.

Step 03

Evenly press the meat mixture into the bottom of the prepared dish, creating a uniform layer.

Step 04

In a separate bowl, stir together cooked pasta shells, shredded cheddar cheese, condensed tomato soup, and milk until fully coated and creamy.

Step 05

Spoon the pasta and cheese mixture evenly over the meat layer, spreading into an even layer.

Step 06

Cover the dish with aluminum foil and bake for 30 minutes.

Step 07

Remove foil and continue baking for an additional 10 to 15 minutes, until the top is bubbling and lightly golden.

Step 08

Allow casserole to rest for several minutes before slicing and serving.

Notes

  1. Let the casserole rest before slicing to help maintain neat portions.

Required Equipment

  • 9×13-inch baking dish
  • Large mixing bowl
  • Measuring cups and spoons
  • Aluminum foil

Allergen Information

Check each ingredient for potential allergens and consult a healthcare professional if needed.
  • Contains milk, wheat (gluten), and may contain traces of soy in processed ingredients.

Nutritional Info (per serving)

This data is provided as a guide and doesn't replace medical advice.
  • Calories: 545
  • Fats: 28 g
  • Carbohydrates: 39 g
  • Proteins: 32 g