Cajun Chicken Broccoli Alfredo

Featured in: Hearty and Delicious Meals

This dish highlights tender chicken breast pieces seasoned with Cajun spices, paired with bright broccoli florets and penne pasta. The combination is brought together in a rich, creamy sauce made from heavy cream, milk, and melted cheese. Each bite balances the spicy warmth from Cajun seasoning and the smoothness of the mozzarella or Monterey Jack cheese. Simple to prepare and satisfying, it's a bold meal perfect for busy evenings when you crave a hint of spice and comforting textures.

A woman is sitting at a table with a plate of food in front of her. The plate contains a dessert with berries on top.
Updated on Sun, 09 Nov 2025 12:23:28 GMT
A delicious Cajun Chicken Broccoli Alfredo dish is served in a black bowl. Pin it
A delicious Cajun Chicken Broccoli Alfredo dish is served in a black bowl. | recipebyme.com

Creamy with a little kick from Cajun spice this chicken broccoli Alfredo is what I pull out when I want a cozy yet bold pasta night at home It has that familiar silky cheese sauce but the smoky heat of Cajun seasoning turns it into something really memorable You get tender broccoli and juicy chicken all tossed with pasta and smothered in saucy goodness

I remember coming up with this after a craving for something creamy plus spicy My husband now asks for it every time he wants comfort food with a twist

Ingredients

  • Chicken breast: about one and a half pounds cut into bite size pieces ensures plenty of protein and makes every forkful hearty Choose firm pink meat for juiciness
  • Salt and fresh ground pepper: to season and bring out flavors Fresh spices make a difference
  • Butter: for a rich silky sauce Opt for real unsalted butter for better control of seasoning
  • Olive oil: balances the richness and helps brown the chicken Well flavored olive oil adds depth
  • Garlic cloves: freshly minced gives a strong aromatic base Freshness matters for that punchy flavor
  • Heavy cream: thirty five percent for luxurious smooth texture Go for real cream not substitutes
  • Milk: to lighten the sauce just a touch and create the perfect consistency Whole milk brings the best creaminess
  • Mozzarella or Monterey Jack cheese: for melty gooey deliciousness Check for fresh soft blocks and grate yourself if possible for better melt
  • Broccoli florets: for color crunch and nutrition Fresh and vibrant green is best
  • Pasta: penne is recommended as it holds sauce in every tube Go for bronze cut if you can spot it
  • Cajun seasoning: for that smoky spicy kick Choose your own spice blend or premade but always check freshness for flavors

Instructions

Season the Chicken:
Let your chicken pieces absorb salt pepper and a generous sprinkle of Cajun seasoning for two to five minutes This allows the flavors to get right into the meat
Prepare Pasta and Broccoli:
Cook your pasta just until al dente according to the box Keep the water boiling fast to avoid mush Meanwhile quickly steam broccoli until it turns bright green and tender but not soft Drain both and set them aside
Brown the Chicken:
In a large pot or skillet heat butter and olive oil over medium high until the butter foams Add chicken in a single layer Let it sear undisturbed for about five minutes per side turning only once to brown while still keeping the inside juicy Remove to a plate and cover
Build the Sauce:
With the pot on medium heat add minced garlic and let it sizzle until fragrant about thirty seconds Stir constantly watch for color without burning
Make It Creamy:
Pour in heavy cream then slowly add milk while stirring This prevents scorching and keeps the sauce smooth Let it come just to a gentle simmer so all the flavors marry together
Add Cheese:
Add freshly grated cheese handful by handful Stir patiently until you see the sauce turn smooth and velvety glossy from fully melted cheese
Finish and Combine:
Return the cooked pasta chicken and broccoli to the pot Toss gently to coat every piece in creamy sauce Taste and balance with more salt pepper or extra Cajun seasoning to hit perfect flavor
Serve:
Dish up while steaming hot Sprinkle a bit more cheese black pepper or fresh parsley on top This adds color and takes the flavor up a notch
A delicious pasta dish with chicken, broccoli, and cheese, served in a black skillet.
A delicious pasta dish with chicken, broccoli, and cheese, served in a black skillet. | recipebyme.com

My favorite part is always the first bite when you get a forkful of zesty sauce chicken and a broccoli floret covered in cheese My kids secretly pick out extra broccoli which tells you just how tasty it is

Storage Tips

Store any leftovers tightly covered in the refrigerator for up to three days Make sure it cools down before sealing To reheat add a splash of milk in a saucepan and warm gently over low heat for the creamiest texture Microwaving is quickest but use lower power and stir in between bursts

Ingredient Substitutions

No chicken Try turkey or even shrimp for a twist Out of cream Half and half will work though the sauce will be a touch lighter Monterey Jack can swap for mozzarella if you prefer a milder cheese Gluten free pasta brands also work but may cook faster

Serving Suggestions

Pile bowls high and maybe finish with a squeeze of lemon for brightness Homemade garlic bread is amazing alongside if you love dunking You can toss in a handful of fresh spinach or chopped sun dried tomatoes for more color

Cultural Notes

Alfredo is traditionally Italian but this version is an American take bringing the creamy pasta to the spicy flavors of Louisiana Cajun kitchens Cajun seasoning adds history and soul making it a fusion classic now a favorite in many homes

Seasonal Adaptations

Swap broccoli for asparagus in spring or add roasted peppers in summer Use sweet potatoes or squash cubes for autumn warmth In winter stir in a handful of frozen peas for extra color

A delicious pasta dish with chicken and broccoli, served in a black bowl.
A delicious pasta dish with chicken and broccoli, served in a black bowl. | recipebyme.com

This recipe always brings warmth and bold flavor to our pasta nights The creamy sauce and hint of spice have made it a loved classic in our house

Recipe FAQs

→ What pasta type works best for this dish?

Penne is recommended, but any sturdy pasta like rigatoni or fusilli holds the creamy sauce well.

→ Can I use a different cheese besides mozzarella or Monterey Jack?

Yes, cheddar or provolone can also be used, though the texture and flavor may vary slightly.

→ How spicy is the Cajun flavor?

The heat level depends on the amount of Cajun seasoning. Start with less and adjust to taste as desired.

→ Is it necessary to steam the broccoli first?

Light steaming helps keep the broccoli bright and tender, but you can cook it briefly in the sauce for extra flavor.

→ Can I substitute chicken breast with other protein?

Chicken thighs, shrimp, or even tofu work well and add different textures to the final dish.

Cajun Chicken Broccoli Alfredo

Chicken, broccoli, and pasta tossed in a creamy, flavorful Cajun-spiced sauce for easy weeknight comfort.

Prep Time
20 min
Cook Time
25 min
Total Time
45 min
By: Sana

Category: Main Dishes

Skill Level: Medium

Cuisine: American

Yield: 4 Servings (Serves 4 generous portions)

Dietary Categories: ~

Ingredients

→ Main Components

01 1 1/2 pounds chicken breast, cut into bite-sized pieces
02 Salt, to season
03 Freshly ground black pepper, to season
04 Cajun seasoning, 1–2 teaspoons or to taste
05 1 tablespoon unsalted butter
06 1 tablespoon olive oil
07 4 garlic cloves, minced
08 1 cup heavy cream (35% milkfat)
09 1 cup whole milk
10 1 1/4 cups grated mozzarella or Monterey Jack cheese
11 1 cup broccoli florets, fresh or lightly steamed
12 1 cup penne pasta, uncooked

Steps

Step 01

Season the chicken pieces evenly with salt, freshly ground black pepper, and Cajun seasoning. Allow to rest briefly for optimum flavor absorption.

Step 02

Boil penne pasta in a large pot of salted water until al dente, then drain and set aside. Steam or blanch broccoli florets until just tender yet brightly colored, then set aside.

Step 03

In a large skillet over medium-high heat, melt butter with olive oil. Add the seasoned chicken and sauté for approximately 5 minutes per side, or until fully cooked and lightly browned. Remove chicken and keep warm.

Step 04

Reduce heat to medium. In the same skillet, add minced garlic and cook until aromatic, about 30 seconds to 1 minute. Pour in heavy cream and gradually add milk, stirring continuously to prevent scorching. Bring to a gentle simmer.

Step 05

Stir in grated mozzarella or Monterey Jack cheese until the sauce is fully melted, smooth, and well blended.

Step 06

Return cooked pasta, sautéed chicken, and broccoli to the skillet. Stir to coat all components in the creamy sauce. Heat through and adjust seasoning with additional Cajun spice, salt, or pepper to taste.

Step 07

Serve immediately while hot and creamy. Optionally garnish with extra grated cheese, freshly ground black pepper, or chopped parsley for presentation.

Notes

  1. For a spicier character, increase the Cajun seasoning or add a pinch of cayenne pepper.

Required Equipment

  • Large skillet or sauté pan
  • Large pot for boiling pasta
  • Colander
  • Steamer basket or small pot for steaming broccoli
  • Knife and cutting board

Allergen Information

Check each ingredient for potential allergens and consult a healthcare professional if needed.
  • Contains dairy and may contain traces of lactose.
  • Contains wheat (gluten) from pasta.

Nutritional Info (per serving)

This data is provided as a guide and doesn't replace medical advice.
  • Calories: 670
  • Fats: 37 g
  • Carbohydrates: 32 g
  • Proteins: 53 g